Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumors are cancerous; benign tumors do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 cancers affect humans.
Tobacco use is the cause of about 22% of cancer deaths. Another 10% is due to obesity, poor diet, lack of physical activity and drinking alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants. In the developing world nearly 20% of cancers are due to infections such as hepatitis B, hepatitis C and human papillomavirus (HPV). These factors act, at least partly, by changing the genes of a cell. Typically many genetic changes are required before cancer develops. Approximately 5–10% of cancers are due to inherited genetic defects from a person's parents. Cancer can be detected by certain signs and symptoms or screening tests. It is then typically further investigated by medical imaging and confirmed by biopsy.
Many cancers can be prevented by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat, and avoiding too much sunlight exposure.
Approx. Rs 6,000 / BottleGet Latest PriceProduct Details:
|Company Name||Hetero Ltd|
Naivex is an antiviral drug designed to treat HIV-1 infection in adults and children 12 years of age and weighing 40 kg or more as part of combination antiretroviral therapy. The drug is recommended for use in patients who have not received therapy ("naive"), and in patients with HAART. In some cases, it can be used in patients with partial resistance to integrase inhibitors.
Manufacturer - Hetero Ltd, India. The active substance is Dolutegravir. Dolutegravir in 2013-2014 is approved in many countries of the world as one of the components of highly active antiretroviral therapy, such as the USA, Canada, Mexico, Brazil, the EU, Russia, Japan, Australia, South Africa.Dolutegravir user guide
Dolutegravir inhibits HIV integration by binding to the active region of integrase and blocking the chain transfer during the integration of retroviral deoxyribonucleic acid (DNA), which is necessary for the HIV replication cycle. In vitro, dolutegravir is slowly separated from the active site of the wild-type DNA integrase complex (half-life of 71 hours).
- Hypersensitivity reactions to dolutegravir (and auxiliary substances).
- Admission of anti-arrhythmic drug Dofetilide (English name Tikosyn)
- Age is less than 12 years and body weight is less than 40 kg
Dolutegravir is rapidly absorbed after ingestion. The average time to reach the maximum concentration is 2-3 hours. When you take 1 time per day, the pharmacokinetic steady state is reached approximately 5 days after the beginning of the oral administration. Food increases the degree and reduces the rate of absorption of dolutegravir. These changes are generally clinically insignificant, so Instgra can be taken regardless of food intake. However, patients infected with HIV-1 with a certain resistance to integrase inhibitors are advised to take Naivex with food.
Co-infection with hepatitis C does not matter for the pharmacokinetics of dolutegravir. Data on co-infection with hepatitis B are limited.
- Impaired immune system. Infrequently: a hypersensitivity reaction, a syndrome of a restoration of immunity.
- Disorders of the psyche. Often: insomnia.
- Disorders of the nervous system. Very often: a headache. Often: dizziness, unusual dreams.
- Disorders of the digestive tract. Very often: nausea, diarrhea. Often: vomiting, flatulence, pain in the upper abdomen. Infrequent: pain in the abdomen, discomfort in the abdomen.
- Disorders of the liver and biliary tract. Infrequently: hepatitis.
- Impaired skin and subcutaneous tissue. Often: rash, itching. General disorders and disorders at the site of administration. Often: fatigue.
- The simultaneous use of dolutegravir and other drugs that inhibit UDP-HT 1A1, UDF-GT1A3, UDF-GT1A9, CYP3A4 and/or Pgp, may increase the concentration of dolutegravir in blood plasma.
- Contraindicated simultaneous reception with dofetilide.
- The simultaneous use of dolutegravir and etravirine is not recommended unless the patient receives simultaneously atazanavir/ritonavir, lopinavir/ritonavir or darunavir/ritonavir.
- The drug should not be administered together with antacids containing polyvalent cations. It is recommended to use dolutegravir 2 hours before or 6 hours after the application of these agents.
- Dolutegravir may increase the concentrations of metformin. It is necessary to monitor patients during therapy, and metformin dosages may need to be adjusted.
Keep the drug in a dry place, protected from sun and inaccessible to children, at a temperature of 15 to 30 ° C. Date of manufacture and shelf life are indicated on the packaging.
Approx. Rs 1,200 / BottleGet Latest PriceProduct Details:
Composition: One tablet consists of an active ingredient - Entecavir (1 mg.) and additional excipients.
Packing: It is delivered in a plastic jar, with a total volume of 30 tablets.
ENTEKOR 1mg is successfully used for the therapy of chronic hepatitis B. A more effective drug, in comparison with interferon, is a new drug formula designed to directly inhibit the protease of the HBV virus.
The benefits of therapy can be presented in this way:
· safety and high efficiency;
ENTEKOR 1MG suppresses the replica of the HBV virus in all three stages, penetrates into the cells affected by the virus, and prevents the splitting of the protein of the viral particle, thus affecting the process of reproduction of the viral RNA.
The recommended dose is 1 tablet per day. Take inside on an empty stomach.
In the presence of pathological processes of the liver or kidneys of various origin, the dosage is selected strictly individually.
The use of the drug may cause adverse reactions in the body, this is:
Entekor (Entecavir 1mg refers to new drugs from the group of nucleoside analogues for the treatment of chronic HBV infection. It is a carboxylic analogue of 2''-deoxyguanosine, rapidly transforming into a cell in an active form, suppressing the replication of HBV in all its three stages - initiation, elongation, termination. Conducted studies of the efficacy of Entecavir in the treatment of patients with chronic hepatitis B showed good tolerability, a high safety profile, a higher efficacy than Lamivudine, and a lack of resistance after 2 years of administration in patients previously untreated with nucleoside analogues. The efficacy of the drug for prescribing patients resistant to Lamivudine was also demonstrated. In all of these cases, Entecavir can be considered the first-line therapy for HBV infection.
Approx. Rs 7,000 / 28 TABGet Latest PriceOther Details:
Approx. Rs 25,000 / TabletGet Latest PriceProduct Details:
|Minimum Order Quantity||1 Tablet|
|Packaging Type||120 Tablets|
|Dose/Strength (ex. 1 mg or 1 ml)||250 mg|
Approx. Rs 13,500 / PackGet Latest PriceProduct Details:
|Packaging Type||30 tablets|
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Approx. Rs 10,000 / StripGet Latest PriceVeenat includes imatinib and is a world class medicine known as protein-tyrosine kinase inhibitor.
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|Dose/Strength||Erlocip 150 mg|
|Packaging Type||30 Tablets|
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|Packaging Type||3*10 Tablets|
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|Packaging Type||2 X 7 TABLETS|
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|Minimum Order Quantity||1 Strip|
|Packaging Type||3 x 10 Tablets|
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|Packaging Type||2 x 7 TABLETS|
Approx. Rs 1,300 / BottleGet Latest PriceProduct Details:
(Tenofovir Disoproxil Fumarate Tablets IP)
Each film coated tablet contains:
Tenofovir Disoproxil Fumarate IP 300 mg
Colours : Indigo Carmine & Titanium Dioxide.
Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. Tenofovir disoproxil fumarate requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir diphosphate inhibits the activity of HIV-1 reverse transcriptase by competing with the natural substrate deoxyadenosine 5`-triphosphate and, after incorporation into DNA, by DNA chain termination. Tenofovir diphosphate is a weak inhibitor of mammalian DNA polymerases alpha and beta, and mitochondrial DNA polymerase gamma.
The pharmacokinetics of tenofovir disoproxil fumarate has been evaluated in healthy volunteers and HIV-1 infected individuals. Tenofovir pharmacokinetics is similar between these populations.
Absorption: Tenofovir disoproxil fumarate is a water soluble diester prodrug of the active ingredient tenofovir. The oral bioavailability of tenofovir from tenofovir disoproxil fumarate in fasted patients is approximately 25%. Following oral administration of a single dose of tenofovir disoproxil fumarate 300 mg to HIV-1 infected patients in the fasted state, maximum serum concentrations (C max ) are achieved in 1.0 ± 0.4 hrs. C max and AUC values are 296 ± 90 ng/mL and 2287 ± 685 ng·hr/mL, respectively.
The pharmacokinetics of tenofovir are dose proportional over a tenofovir disoproxil fumarate dose range of 75 to 600 mg and are not affected by repeated dosing.
Effects of Food on Oral Absorption: Administration of tenofovir disoproxil fumarate following a high-fat meal (~700 to 1000 kcal containing 40 to 50% fat) increases the oral bioavailability, with an increase in tenofovir AUC of approximately 40% and an increase in C max of approximately 14%. However, administration of tenofovir disoproxil fumarate with a light meal did not have a significant effect on the pharmacokinetics of tenofovir when compared to fasted administration of the drug. Food delays the time to tenofovir C max by approximately 1 hour.
Distribution: In vitro binding of tenofovir to human plasma or serum proteins is less than 0.7 and 7.2%, respectively, over the tenofovir concentration range 0.01 to 25 μg/mL. The volume of distribution at steady state is 1.3 ± 0.6 L/kg and 1.2 ± 0.4 L/kg, following intravenous administration of tenofovir 1.0 mg/kg and 3.0 mg/kg.
Metabolism and Elimination: In vitro studies indicate that neither tenofovir disoproxil nor tenofovir are substrates of CYP450 enzymes.
Following IV administration of tenofovir, approximately 70-80% of the dose is recovered in the urine as unchanged tenofovir within 72 hours of dosing. Following single dose, oral administration of tenofovir disoproxil fumarate, the terminal elimination half-life of tenofovir is approximately 17 hours. After multiple oral doses of tenofovir disoproxil fumarate 300 mg once daily (under fed conditions), 32 ± 10% of the administered dose is recovered in urine over 24 hours.
Tenofovir is eliminated by a combination of glomerular filtration and active tubular secretion.
INDICATIONS : TUDOFOVIR is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
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|Minimum Order Quantity||1 Pack|
Aprepitant is used with other medications to prevent nausea and vomiting that may occur within 24 hours after receiving cancer chemotherapy treatment. It is also used with other medications to prevent delayed nausea and vomiting that may occur several days after receiving certain chemotherapy medications. Aprepitant is also used alone to prevent nausea and vomiting caused by surgery. Aprepitant is not used to treat nausea and vomiting that you already have. Aprepitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.How should this medicine be used?
Aprepitant comes as a capsule to take by mouth. To prevent nausea and vomiting caused by cancer chemotherapy, aprepitant is usually taken once daily, with or without food, during the first few days of your cancer chemotherapy treatment. You will probably take aprepitant 1 hour before your first dose of chemotherapy, and then each morning for the next 2 days. To prevent nausea and vomiting caused by surgery, aprepitant is usually taken as one dose within 3 hours before the start of surgery. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take aprepitant exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Aprepitant capsules come in two different strengths. Your doctor may prescribe both of the strengths for you to take at different times. You should be careful to take the right strength at the right time as directed by your doctor.
Aprepitant only works to prevent nausea and vomiting. Call your doctor if you already have these symptoms and do not begin to take aprepitant.
When used to prevent nausea and vomiting caused by cancer chemotherapy, aprepitant is usually used only during the first 3 days of the chemotherapy treatment cycles. Do not continue taking aprepitant longer than instructed by your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.What side effects can this medication cause Aprepitant may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Approx. Rs 5,000 / PackGet Latest PriceWhy is this medication prescribed?
Bicalutamide is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (cancer that started in the prostate and has spread to other parts of the body). Bicalutamide is in a class of medications called nonsteroidal antiandrogens. It works by blocking the effect of androgen (a male hormone), to stop the growth and spread of cancer cells.How should this medicine be used?
Bicalutamide comes as a tablet to take by mouth. It is usually taken with or without food once a day, either in the morning or evening. Take bicalutamide at around the same time every day. You should begin taking bicalutamide on the same day you begin injecting the luteinizing hormone-releasing hormone. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take bicalutamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Bicalutamide along with the luteinizing hormone-releasing hormone may help stop the growth and spread of cancer cells but does not cure prostate cancer. Continue to take both bicalutamide and the luteinizing hormone-releasing hormone even if you feel better. Do not stop taking these medications without talking to your doctor.Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
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Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.How Carboplatin Is Given:
Important things to remember about the side effects of Carboplatin:
The following side effects are common (occurring in greater than 30%) for patients taking Carboplatin:
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Cisplatin is used to treat various types of cancer. It is a chemotherapy drug that contains platinum. It is used alone or in combination with other medications to slow or stop cancer cell growth.How to use cisplatin intravenous
This medication is usually given by injection into a vein by a health care professional. The dosage is based on your medical condition, body size, and response to therapy. Courses of cisplatin treatment should not be given more often than once every 3 to 4 weeks. Consult your doctor or pharmacist for more details.
During treatment with this medication, it is important that you take in more fluids than usual and pass urine frequently to help avoid kidney side effects. Intravenous fluids should be given with this medication. Also, ask your doctor how much fluid you should drink and follow these instructions carefully.
If this medication comes into contact with your skin, wash your skin right away and completely with soap and water.Side Effects
See also Warnings.
Nausea, vomiting, loss of appetite, diarrhea, and loss of taste may occur. Nausea and vomiting can be quite severe and persistent. Drug therapy is used to prevent or relieve nausea and vomiting. Not eating before your treatment may help relieve vomiting. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Temporary hair loss may occur. Normal hair growth should return after treatment has ended.Precautions
Before using cisplatin, tell your doctor or pharmacist if you are allergic to it; or to carboplatin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
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|Minimum Order Quantity||1 Pack|
|Packaging Type||Glass Bottle|
Approx. Rs 12,000 / BottleGet Latest PriceProduct Description
Docetaxel is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as a “plant alkaloid,” a “taxane” and an “antimicrotubule agent.” (For more detail, see “How this drug works” section below)What Docetaxel Is Used For:
Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.How Docetaxel Is Given:
Important things to remember about the side effects of docetaxel:
Approx. Rs 14,000 / PackGet Latest PriceUses Doxorubicin 10mg injection is used in the treatment of blood cancer How it works Doxorubicin 10mg injection works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.Common side effects Nausea, Vomiting, Weakness, Infection, Stomatitis (Inflammation of the mouth), Hair loss, Hand-foot syndrome, Decreased white blood cell count (neutrophils), Decreased appetite, Decreased blood cells (red cells, white cells, and platelets), Decreased white blood cell count, Fever, Mucosal inflammation, Anemia
Approx. Rs 3,000 / BottleGet Latest PriceProduct Details:
Temirazer is a far-reaching powerful antiretroviral sedate for the treatment of HIV-1 and HIV-2 contaminations in patients more than 18 years old. Can be taken correspondingly with other comparative medications. Temirazer is doled out to a gathering of non-nucleoside inhibitors with turnaround transcriptase, otherwise called a protease inhibitor. The medication contains two fundamental dynamic fixings - tenofovir and emtricitabine, because of which the medication has a viable impact in the battle against HIV contaminations, keeping the infection from spreading in the host's body.
It ought to be noticed that Temirazer does not totally keep the danger of HIV transmission, but rather is a successful method to anticipate it. After various investigations in the United States, it has been demonstrated that this medication helps battle AIDS, and on the off chance that it is clung to, the danger of contracting HIV is decreased by 73%. It is additionally realized that Temirazer is an inhibitor of the hepatitis B infection, yet it isn't prescribed to utilize the medication with its endless shape. In the wake of finishing the course of taking Temirazer, individuals with HIV and ceaseless hepatitis B ought to be checked by their specialist inside a couple of months.
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|Packaging Type||6 TABLETS|
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|Packaging Size||1 X 10 TABLETS|
|Dose/Strength (ex. 1 mg or 1 ml)||Everolimus(10 Mg)|
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Approx. Rs 6,000 / PackGet Latest PriceWhat Anastrozole Is Used For:
Note: If a drug has been approved for one use, physicians sometimes elect to use this same drug for other problems if they believe it might be helpful.How Anastrozole Is Given:
The amount of anastrozole that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and how long you will be taking anastrozole.Side Effects:
Important things to remember about the side effects of anastrozole:
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|Minimum Order Quantity||1 Box|
|Packaging Type||10 Tab|
Treating certain types of breast, colon, or colorectal cancer in some patients. It may be used alone or with other medicines in some cases.
Capecitabine is an antimetabolite. It works by interfering with the production of proteins necessary for cancer cell growth and reproduction.Do NOT use capecitabine if:
Contact your doctor or health care provider right away if any of these apply to you.Before using capecitabine:
Some medical conditions may interact with capecitabine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with capecitabine. Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if capecitabine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.How to use capecitabine:
Use capecitabine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use capecitabine.
Approx. Rs 121.5 / StripGet Latest PriceProduct Details:
|Minimum Order Quantity||1 Strip|
|Packaging Type||10 capsules|
|Dose/Strength (ex. 1 mg or 1 ml)||250mg|
Natclovir is an antiviral agent. It works by blocking reproduction of the CMV virus. It helps control CMV retinitis and decrease the risk of blindness.WHAT IS THE USE OF NATCLOVIR 250 MG CAPSULES ?
It is used to prevent disease caused by a virus called cytomegalovirus (CMV) in people who have received organ or bone marrow transplants. CMV disease can lead to serious infections in the body, including an infection in the eye, called CMV retinitis, that can cause blindness. Ganciclovir 250 mg is also used to treat people with weakened immune systems (including people with AIDS) who have CMV retinitis.WHAT ARE THE POSSIBLE SIDE-EFFECTS OF NATCLOVIR 250 MG CAPSULES ?
Diarrhea, upset stomach, dizziness, drowsiness, unsteadiness, shaking (tremors), or pain/redness/irritation at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (such as confusion, hallucinations), signs of kidney problems (such as change in the amount of urine), seizures.This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.
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